Resection or Ablative Treatment of Small Renal Tumors, a Multicenter Randomized Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Ablative treatments are believed to have a lower rate of complications, shorter hospital stays, and fewer interventions with benign PAD compared to partial nephrectomies in small kidney cancer lesions. The purpose of the study is to compare complications, the frequency of residual tumors, impact on kidney function, differences in quality of life, and health economic factors in a randomised study. We will also compare the oncological outcomes, including survival and recurrence of kidney cancer.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:

• Age 18 - 99 years

• Patient suitable based on clinical status for both ablative treatment and surgery

• Primary kidney tumor

• Tumor size ≤ 3 cm

• Clinical stage of the tumor T1a (no macroscopic vascular or extrarenal invasion)

• Tumor location suitable for both ablative treatment and resection

• Absence of radiological signs of metastasis

• Biopsy with malignant pathological analysis (PAD)

• ISUP grade I-III

Locations
Other Locations
Sweden
Karolinska University Hospital
RECRUITING
Stockholm
Contact Information
Primary
Anders Kjellman, MD, PhD
anders.kjellman@regionstockholm.se
+46736995258
Backup
Per-Olof Lundgren, MD, PhD
Time Frame
Start Date: 2024-01-31
Estimated Completion Date: 2037-12
Participants
Target number of participants: 300
Treatments
Experimental: Ablation
Ablative treatment of small kidney cancer lesion, could be given with radiofrequency, microwawe or cryoablation
Active_comparator: Partial nephrectomy
Surgical resection with open or laparoscopic technique
Related Therapeutic Areas
Sponsors
Leads: Karolinska University Hospital

This content was sourced from clinicaltrials.gov